N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
TL;DR: N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide (CAS 357939-37-8) is a chemical compound with molecular formula C15H11ClN2OS and molecular weight 302.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-N-(3-chloro-2-methylphenyl)-2-cyano-3-thiophen-2-ylprop-2-enamide
Also Known As: (Z)-N-(3-Chloro-2-methylphenyl)-2-cyano-3-thiophen-2-ylprop-2-enamide, N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
| Molecular Formula | C15H11ClN2OS |
|---|---|
| Molecular Weight | 302.03 g/mol |
| LogP | 4.2556 |
| Topological Polar Surface Area | 52.89 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 302.02808 |
| Heavy Atoms | 20 |
| Complexity | 699.15875 |
Chemical Identifiers
| CAS Number | 357939-37-8 |
|---|---|
| SMILES | CC1=C(C=CC=C1Cl)NC(=O)/C(=C\C2=CC=CS2)/C#N |
Product Overview
N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide (CAS 357939-37-8), with molecular formula C15H11ClN2OS and molecular weight 302.03 g/mol. IUPAC: (Z)-N-(3-chloro-2-methylphenyl)-2-cyano-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
Property Insights of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
The XLogP value of 4.2556 indicates that N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.89 Ų, N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
The CAS number of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is 357939-37-8.
What is the molecular formula of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
The molecular formula of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is C15H11ClN2OS.
What is the molecular weight of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
The molecular weight of N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is 302.03 g/mol.
Where can I buy N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
You can request a quote for N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-chloro-2-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.