RNase L-IN-2
TL;DR: RNase L-IN-2 (CAS 357618-26-9) is a chemical compound with molecular formula C16H14N2O2S and molecular weight 298.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3-hydroxyphenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
Also Known As: RNase L-IN-2, 5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one, BIM-0038649.P001, 2-(3-hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one, BRD-K13934231-001-01-9
| Molecular Formula | C16H14N2O2S |
|---|---|
| Molecular Weight | 298.08 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 89.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 298.0776 |
| Heavy Atoms | 21 |
| Complexity | 467.0 |
Chemical Identifiers
| CAS Number | 357618-26-9 |
|---|---|
| SMILES | C1CCC2=C(C1)C3=C(S2)N=C(NC3=O)C4=CC(=CC=C4)O |
| InChIKey | YEBWEMIJOWUBEM-UHFFFAOYSA-N |
Product Overview
RNase L-IN-2 (CAS 357618-26-9), with molecular formula C16H14N2O2S and molecular weight 298.08 g/mol. IUPAC: 2-(3-hydroxyphenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one.
Chemical Property Profile of RNase L-IN-2
Property Insights of RNase L-IN-2
The XLogP value of 3.2 indicates that RNase L-IN-2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 89.9 Ų falls within the moderate polarity range, balancing permeability and solubility for RNase L-IN-2. Following Lipinski's Rule of Five, RNase L-IN-2 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RNase L-IN-2?
The CAS number of RNase L-IN-2 is 357618-26-9.
What is the molecular formula of RNase L-IN-2?
The molecular formula of RNase L-IN-2 is C16H14N2O2S.
What is the molecular weight of RNase L-IN-2?
The molecular weight of RNase L-IN-2 is 298.08 g/mol.
Where can I buy RNase L-IN-2?
You can request a quote for RNase L-IN-2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RNase L-IN-2?
Yes, KEHONG BIO provides custom synthesis services for RNase L-IN-2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.