Benazepril-amlodipine
TL;DR: Benazepril-amlodipine (CAS 357437-90-2) is a chemical compound with molecular formula C44H53ClN4O10 and molecular weight 832.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Lotrel, Benazepril-amlodipine, amlodipine/benazepril, Amlodipine - benazepril, Amlodipine mixture with Benazepril
| Molecular Formula | C44H53ClN4O10 |
|---|---|
| Molecular Weight | 832.35 g/mol |
| LogP | 4.8394 |
| Topological Polar Surface Area | 195.82 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 17 |
| Exact Mass | 832.34503 |
| Heavy Atoms | 59 |
| Complexity | 2003.6118 |
Chemical Identifiers
| CAS Number | 357437-90-2 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=CC=CC=C3N(C2=O)CC(=O)O |
Product Overview
Benazepril-amlodipine (CAS 357437-90-2), with molecular formula C44H53ClN4O10 and molecular weight 832.35 g/mol. IUPAC: 2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Benazepril-amlodipine
Property Insights of Benazepril-amlodipine
The XLogP value of 4.8394 indicates that Benazepril-amlodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 195.82 Ų indicates high polarity, suggesting Benazepril-amlodipine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Benazepril-amlodipine has 4 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Benazepril-amlodipine?
The CAS number of Benazepril-amlodipine is 357437-90-2.
What is the molecular formula of Benazepril-amlodipine?
The molecular formula of Benazepril-amlodipine is C44H53ClN4O10.
What is the molecular weight of Benazepril-amlodipine?
The molecular weight of Benazepril-amlodipine is 832.35 g/mol.
Where can I buy Benazepril-amlodipine?
You can request a quote for Benazepril-amlodipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Benazepril-amlodipine?
Yes, KEHONG BIO provides custom synthesis services for Benazepril-amlodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.