Varenicline Impurity 36 structure

Varenicline Impurity 36

TL;DR: Varenicline Impurity 36 (CAS 357424-07-8) is a chemical compound with molecular formula C13H13N3O2 and molecular weight 243.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4(9),10-triene-6,7-dione

Also Known As: Varenicline Impurity 36, Varenicline Impurity 13 HCl, 4,6,7,8,9,10-Hexahydro-6,10-methano-1H-pyrazino[2,3-h][3]benzazepine-2,3-dione Hydrochloride, 4,6,7,8,9,10-Hexahydro-1H-6,10-methanoazepino[4,5-g]quinoxaline-2,3-dione

CAS: 357424-07-8
Molecular Formula C13H13N3O2
Molecular Weight 243.10 g/mol
LogP 0.3905
Topological Polar Surface Area 77.75 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 3
Rotatable Bonds 0
Exact Mass 243.10077
Heavy Atoms 18
Complexity 696.4009

Chemical Identifiers

CAS Number 357424-07-8
SMILES C1C2CNCC1C3=CC4=C(C=C23)NC(=O)C(=O)N4

Product Overview

Varenicline Impurity 36 (CAS 357424-07-8), with molecular formula C13H13N3O2 and molecular weight 243.10 g/mol. IUPAC: 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4(9),10-triene-6,7-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Varenicline Impurity 36

XLogP
0.3905
TPSA (Topological Polar Surface Area)
77.75
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
3
Rotatable Bonds
0
Heavy Atoms
18
Complexity
696.4009
Exact Mass
243.10077
Monoisotopic Mass
243.10077
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Varenicline Impurity 36

The XLogP value of 0.3905 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Varenicline Impurity 36. The TPSA of 77.75 Ų falls within the moderate polarity range, balancing permeability and solubility for Varenicline Impurity 36. Following Lipinski's Rule of Five, Varenicline Impurity 36 has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Varenicline Impurity 36?

The CAS number of Varenicline Impurity 36 is 357424-07-8.

What is the molecular formula of Varenicline Impurity 36?

The molecular formula of Varenicline Impurity 36 is C13H13N3O2.

What is the molecular weight of Varenicline Impurity 36?

The molecular weight of Varenicline Impurity 36 is 243.10 g/mol.

Where can I buy Varenicline Impurity 36?

You can request a quote for Varenicline Impurity 36 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Varenicline Impurity 36?

Yes, KEHONG BIO provides custom synthesis services for Varenicline Impurity 36 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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