BIM-0012586.P001
TL;DR: BIM-0012586.P001 (CAS 357293-36-8) is a chemical compound with molecular formula C17H18BrF3N4O2S and molecular weight 478.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-bromo-N-(oxolan-2-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: BIM-0012586.P001, 3-bromo-N-((tetrahydrofuran-2-yl)methyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide, 3-bromo-N-(tetrahydrofuran-2-ylmethyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide, 3-bromo-N-(oxolan-2-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide, 3-bromo-N-(tetrahydro-2-furanylmethyl)-5-(2-thienyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide
| Molecular Formula | C17H18BrF3N4O2S |
|---|---|
| Molecular Weight | 478.03 g/mol |
| LogP | 4.2762 |
| Topological Polar Surface Area | 68.18 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 478.0286 |
| Heavy Atoms | 28 |
| Complexity | 849.44995 |
Chemical Identifiers
| CAS Number | 357293-36-8 |
|---|---|
| SMILES | C1CC(OC1)CNC(=O)C2=NN3C(CC(NC3=C2Br)C4=CC=CS4)C(F)(F)F |
Product Overview
BIM-0012586.P001 (CAS 357293-36-8), with molecular formula C17H18BrF3N4O2S and molecular weight 478.03 g/mol. IUPAC: 3-bromo-N-(oxolan-2-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of BIM-0012586.P001
Property Insights of BIM-0012586.P001
The XLogP value of 4.2762 indicates that BIM-0012586.P001 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.18 Ų falls within the moderate polarity range, balancing permeability and solubility for BIM-0012586.P001. Following Lipinski's Rule of Five, BIM-0012586.P001 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of BIM-0012586.P001?
The CAS number of BIM-0012586.P001 is 357293-36-8.
What is the molecular formula of BIM-0012586.P001?
The molecular formula of BIM-0012586.P001 is C17H18BrF3N4O2S.
What is the molecular weight of BIM-0012586.P001?
The molecular weight of BIM-0012586.P001 is 478.03 g/mol.
Where can I buy BIM-0012586.P001?
You can request a quote for BIM-0012586.P001 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for BIM-0012586.P001?
Yes, KEHONG BIO provides custom synthesis services for BIM-0012586.P001 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.