Tetrahydrothiamine pyrophosphate structure

Tetrahydrothiamine pyrophosphate

TL;DR: Tetrahydrothiamine pyrophosphate (CAS 35728-83-7) is a chemical compound with molecular formula C12H22N4O7P2S and molecular weight 428.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate

Also Known As: Tetrahydro-tpp, Tetrahydrothiamine diphosphate, Tetrahydrothiamine pyrophosphate, Tetrahydrothiamin pyrophosphate, 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate

CAS: 35728-83-7
Molecular Formula C12H22N4O7P2S
Molecular Weight 428.07 g/mol
LogP -3.7
Topological Polar Surface Area 194.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 12
Rotatable Bonds 8
Exact Mass 428.06845
Heavy Atoms 26
Complexity 568.0

Chemical Identifiers

CAS Number 35728-83-7
SMILES CC1C(SCN1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O
InChIKey QMLRZDVHAMEWFV-UHFFFAOYSA-N

Product Overview

Tetrahydrothiamine pyrophosphate (CAS 35728-83-7), with molecular formula C12H22N4O7P2S and molecular weight 428.07 g/mol. IUPAC: 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tetrahydrothiamine pyrophosphate

XLogP
-3.7
TPSA (Topological Polar Surface Area)
194.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
12
Rotatable Bonds
8
Heavy Atoms
26
Complexity
568.0
Exact Mass
428.06845
Monoisotopic Mass
428.06845
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tetrahydrothiamine pyrophosphate

The XLogP value of -3.7 indicates that Tetrahydrothiamine pyrophosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 194.0 Ų indicates high polarity, suggesting Tetrahydrothiamine pyrophosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tetrahydrothiamine pyrophosphate has 4 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tetrahydrothiamine pyrophosphate?

The CAS number of Tetrahydrothiamine pyrophosphate is 35728-83-7.

What is the molecular formula of Tetrahydrothiamine pyrophosphate?

The molecular formula of Tetrahydrothiamine pyrophosphate is C12H22N4O7P2S.

What is the molecular weight of Tetrahydrothiamine pyrophosphate?

The molecular weight of Tetrahydrothiamine pyrophosphate is 428.07 g/mol.

Where can I buy Tetrahydrothiamine pyrophosphate?

You can request a quote for Tetrahydrothiamine pyrophosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tetrahydrothiamine pyrophosphate?

Yes, KEHONG BIO provides custom synthesis services for Tetrahydrothiamine pyrophosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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