Pemetrexed (sodium salt hydrate) structure

Pemetrexed (sodium salt hydrate)

TL;DR: Pemetrexed (sodium salt hydrate) (CAS 35717-41-0) is a chemical compound with molecular formula C49H88Cl2NO7P and molecular weight 903.57 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[3-[bis(2-chloroethyl)amino-phenoxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate

Also Known As: Pemetrexed (sodium salt hydrate), N-CARBOBENZOXYAMINOACETONITRILE, 3-({[bis(2-chloroethyl)amino](phenoxy)phosphoryl}oxy)-2-(octadecanoyloxy)propyl octadecanoate, [3-[bis(2-chloroethyl)amino-phenoxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate, 3-(((bis(2-chloroethyl)amino)(phenoxy)phosphoryl)oxy)propane-1,2-diyl distearate

CAS: 35717-41-0
Molecular Formula C49H88Cl2NO7P
Molecular Weight 903.57 g/mol
LogP 19.4
Topological Polar Surface Area 91.4 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 47
Exact Mass 903.56757
Heavy Atoms 60
Complexity 1010.0

Chemical Identifiers

CAS Number 35717-41-0
SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(N(CCCl)CCCl)OC1=CC=CC=C1)OC(=O)CCCCCCCCCCCCCCCCC
InChIKey HVQZYCXYFLFKKQ-UHFFFAOYSA-N

Product Overview

Pemetrexed (sodium salt hydrate) (CAS 35717-41-0), with molecular formula C49H88Cl2NO7P and molecular weight 903.57 g/mol. IUPAC: [3-[bis(2-chloroethyl)amino-phenoxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pemetrexed (sodium salt hydrate)

XLogP
19.4
TPSA (Topological Polar Surface Area)
91.4
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
47
Heavy Atoms
60
Complexity
1010.0
Exact Mass
903.56757
Monoisotopic Mass
903.56757
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pemetrexed (sodium salt hydrate)

The XLogP value of 19.4 indicates that Pemetrexed (sodium salt hydrate) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Pemetrexed (sodium salt hydrate). Following Lipinski's Rule of Five, Pemetrexed (sodium salt hydrate) has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pemetrexed (sodium salt hydrate)?

The CAS number of Pemetrexed (sodium salt hydrate) is 35717-41-0.

What is the molecular formula of Pemetrexed (sodium salt hydrate)?

The molecular formula of Pemetrexed (sodium salt hydrate) is C49H88Cl2NO7P.

What is the molecular weight of Pemetrexed (sodium salt hydrate)?

The molecular weight of Pemetrexed (sodium salt hydrate) is 903.57 g/mol.

Where can I buy Pemetrexed (sodium salt hydrate)?

You can request a quote for Pemetrexed (sodium salt hydrate) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pemetrexed (sodium salt hydrate)?

Yes, KEHONG BIO provides custom synthesis services for Pemetrexed (sodium salt hydrate) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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