Spirilene
TL;DR: Spirilene (CAS 357-66-4) is a chemical compound with molecular formula C24H28FN3O and molecular weight 393.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-[4-(4-fluorophenyl)pent-3-enyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Also Known As: Spirilene, Isospirilene, Espirileno, Spirilenum, Spirilene [INN:BAN]
| Molecular Formula | C24H28FN3O |
|---|---|
| Molecular Weight | 393.22 g/mol |
| LogP | 4.6 |
| Topological Polar Surface Area | 35.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 393.22165 |
| Heavy Atoms | 29 |
| Complexity | 585.0 |
Chemical Identifiers
| CAS Number | 357-66-4 |
|---|---|
| SMILES | CC(=CCCN1CCC2(CC1)C(=O)NCN2C3=CC=CC=C3)C4=CC=C(C=C4)F |
| InChIKey | YBPJJOQQWQASHM-UHFFFAOYSA-N |
Product Overview
Spirilene (CAS 357-66-4), with molecular formula C24H28FN3O and molecular weight 393.22 g/mol. IUPAC: 8-[4-(4-fluorophenyl)pent-3-enyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.
Chemical Property Profile of Spirilene
Property Insights of Spirilene
The XLogP value of 4.6 indicates that Spirilene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.6 Ų, Spirilene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Spirilene has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Spirilene?
The CAS number of Spirilene is 357-66-4.
What is the molecular formula of Spirilene?
The molecular formula of Spirilene is C24H28FN3O.
What is the molecular weight of Spirilene?
The molecular weight of Spirilene is 393.22 g/mol.
Where can I buy Spirilene?
You can request a quote for Spirilene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Spirilene?
Yes, KEHONG BIO provides custom synthesis services for Spirilene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.