Icajine
TL;DR: Icajine (CAS 35699-20-8) is a chemical compound with molecular formula C22H26N2O2 and molecular weight 350.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(10S,22R,23R,24S)-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraen-20-one
Also Known As: Icajine, KST-1A4156, Strychnidinium, 16-hydroxy-19-methyl-, (4ar,12as,12br,12cs)-15-methyl-4a,5,12,12a,12b,12c-hexahydro-11h-6a,4-(ethanoiminomethano)-1-oxa-10b-azacyclohepta[1,2,3-cd]fluoranthen-6(2h)-one, (10S,22R,23R,24S)-4-Methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraen-20-one
| Molecular Formula | C22H26N2O2 |
|---|---|
| Molecular Weight | 350.20 g/mol |
| LogP | 1.5 |
| Topological Polar Surface Area | 32.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 350.19943 |
| Heavy Atoms | 26 |
| Complexity | 661.0 |
Chemical Identifiers
| CAS Number | 35699-20-8 |
|---|---|
| SMILES | CN1CCC23[C@@H]4[C@@H]5[C@H](CCN4C6=CC=CC=C62)OCC=C(C1)[C@@H]5CC3=O |
| InChIKey | JJLDCCAQWIHRLV-PNRRXULYSA-N |
Product Overview
Icajine (CAS 35699-20-8), with molecular formula C22H26N2O2 and molecular weight 350.20 g/mol. IUPAC: (10S,22R,23R,24S)-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraen-20-one.
Chemical Property Profile of Icajine
Property Insights of Icajine
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Icajine. With a topological polar surface area (TPSA) of 32.8 Ų, Icajine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Icajine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Icajine?
The CAS number of Icajine is 35699-20-8.
What is the molecular formula of Icajine?
The molecular formula of Icajine is C22H26N2O2.
What is the molecular weight of Icajine?
The molecular weight of Icajine is 350.20 g/mol.
Where can I buy Icajine?
You can request a quote for Icajine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Icajine?
Yes, KEHONG BIO provides custom synthesis services for Icajine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.