![1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea structure](/static/products/356/356586-16-8.png)
1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
TL;DR: 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea (CAS 356586-16-8) is a chemical compound with molecular formula C18H17F3N4OS and molecular weight 394.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methyl-2-pyridinyl)-3-[3-(trifluoromethyl)phenyl]urea
Also Known As: 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea, 1-(5-methyl-4,5-dihydrothiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea
| Molecular Formula | C18H17F3N4OS |
|---|---|
| Molecular Weight | 394.11 g/mol |
| LogP | 4.93862 |
| Topological Polar Surface Area | 57.59 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 394.1075 |
| Heavy Atoms | 27 |
| Complexity | 884.90564 |
Chemical Identifiers
| CAS Number | 356586-16-8 |
|---|---|
| SMILES | CC1CN=C(S1)N(C2=C(C=CC=N2)C)C(=O)NC3=CC=CC(=C3)C(F)(F)F |
Product Overview
1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea (CAS 356586-16-8), with molecular formula C18H17F3N4OS and molecular weight 394.11 g/mol. IUPAC: 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methyl-2-pyridinyl)-3-[3-(trifluoromethyl)phenyl]urea.
Chemical Property Profile of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
Property Insights of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
The XLogP value of 4.93862 indicates that 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.59 Ų, 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea?
The CAS number of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea is 356586-16-8.
What is the molecular formula of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea?
The molecular formula of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea is C18H17F3N4OS.
What is the molecular weight of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea?
The molecular weight of 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea is 394.11 g/mol.
Where can I buy 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea?
You can request a quote for 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1-(3-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.