N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide
TL;DR: N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide (CAS 356586-01-1) is a chemical compound with molecular formula C16H16F6N2O2S and molecular weight 414.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5,5-dimethyl-4H-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide
Also Known As: N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide, N-(5,5-dimethyl-4,5-dihydrothiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide, N-(5,5-dimethyl-4H-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide
| Molecular Formula | C16H16F6N2O2S |
|---|---|
| Molecular Weight | 414.08 g/mol |
| LogP | 4.6504 |
| Topological Polar Surface Area | 41.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 414.08368 |
| Heavy Atoms | 27 |
| Complexity | 713.91144 |
Chemical Identifiers
| CAS Number | 356586-01-1 |
|---|---|
| SMILES | CC1(CN=C(S1)N(C2=CC=C(C=C2)OC)C(=O)C(C(F)(F)F)C(F)(F)F)C |
Product Overview
N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide (CAS 356586-01-1), with molecular formula C16H16F6N2O2S and molecular weight 414.08 g/mol. IUPAC: N-(5,5-dimethyl-4H-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide.
Chemical Property Profile of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide
Property Insights of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide
The XLogP value of 4.6504 indicates that N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.9 Ų, N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide?
The CAS number of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide is 356586-01-1.
What is the molecular formula of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide?
The molecular formula of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide is C16H16F6N2O2S.
What is the molecular weight of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide?
The molecular weight of N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide is 414.08 g/mol.
Where can I buy N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide?
You can request a quote for N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)-3,3,3-trifluoro-N-(4-methoxyphenyl)-2-(trifluoromethyl)propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.