Megestrol
TL;DR: Megestrol (CAS 3562-63-8) is a chemical compound with molecular formula C22H30O3 and molecular weight 342.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: megestrol, Megestrolo, Megestrolum, Chronopil, Magestin
| Molecular Formula | C22H30O3 |
|---|---|
| Molecular Weight | 342.22 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 54.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 342.21948 |
| Heavy Atoms | 25 |
| Complexity | 717.0 |
| Solubility | WHITE OR ALMOST WHITE, CRYSTALLINE POWDER; SPARINGLY SOL IN ALC; SLIGHTLY SOL IN ETHER & FIXED OILS; SOL IN ACETONE; VERY SOL IN CHLOROFORM /ACETATE/ |
Chemical Identifiers
| CAS Number | 3562-63-8 |
|---|---|
| SMILES | CC1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C |
| InChIKey | VXIMPSPISRVBPZ-NWUMPJBXSA-N |
Patent-Derived Application Labels
Derived from 15 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Megestrol (CAS 3562-63-8), with molecular formula C22H30O3 and molecular weight 342.22 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of Megestrol
Property Insights of Megestrol
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Megestrol. With a topological polar surface area (TPSA) of 54.4 Ų, Megestrol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Megestrol has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Megestrol?
The CAS number of Megestrol is 3562-63-8.
What is the molecular formula of Megestrol?
The molecular formula of Megestrol is C22H30O3.
What is the molecular weight of Megestrol?
The molecular weight of Megestrol is 342.22 g/mol.
Where can I buy Megestrol?
You can request a quote for Megestrol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Megestrol?
Yes, KEHONG BIO provides custom synthesis services for Megestrol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.