2-Chloro-4-(dimethylamino)-5-fluoropyrimidine
TL;DR: 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine (CAS 355829-23-1) is a chemical compound with molecular formula C6H7ClFN3 and molecular weight 175.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-5-fluoro-N,N-dimethylpyrimidin-4-amine
Also Known As: 2-chloro-5-fluoro-N,N-dimethylpyrimidin-4-amine, 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine, CHEMBRDG-BB 6083647, 1467AE, 2-chloro-5-fluoro-N,N-dimethyl-4-pyrimidinamine
| Molecular Formula | C6H7ClFN3 |
|---|---|
| Molecular Weight | 175.03 g/mol |
| LogP | 1.3351 |
| Topological Polar Surface Area | 29.02 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 175.03125 |
| Heavy Atoms | 11 |
| Complexity | 264.00436 |
Chemical Identifiers
| CAS Number | 355829-23-1 |
|---|---|
| SMILES | CN(C)C1=NC(=NC=C1F)Cl |
Product Overview
2-Chloro-4-(dimethylamino)-5-fluoropyrimidine (CAS 355829-23-1), with molecular formula C6H7ClFN3 and molecular weight 175.03 g/mol. IUPAC: 2-chloro-5-fluoro-N,N-dimethylpyrimidin-4-amine.
Chemical Property Profile of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine
Property Insights of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine
The XLogP value of 1.3351 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine. With a topological polar surface area (TPSA) of 29.02 Ų, 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine?
The CAS number of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine is 355829-23-1.
What is the molecular formula of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine?
The molecular formula of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine is C6H7ClFN3.
What is the molecular weight of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine?
The molecular weight of 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine is 175.03 g/mol.
Where can I buy 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine?
You can request a quote for 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-4-(dimethylamino)-5-fluoropyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.