2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine
TL;DR: 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine (CAS 355821-33-9) is a chemical compound with molecular formula C14H14ClFN4 and molecular weight 292.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine
Also Known As: 2-chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine, 2-chloro-5-fluoro-4-(4-phenylpiperazinyl)pyrimidine, 2-Chloro-5-fluoro-4-(4-phenyl-1-piperazinyl)pyrimidine, 2-Chloro-5-fluoro-4-(4-phenyl-piperazin-1-yl)-pyrimidine
| Molecular Formula | C14H14ClFN4 |
|---|---|
| Molecular Weight | 292.09 g/mol |
| LogP | 2.5957 |
| Topological Polar Surface Area | 32.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 292.0891 |
| Heavy Atoms | 20 |
| Complexity | 584.9827 |
Chemical Identifiers
| CAS Number | 355821-33-9 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C3=NC(=NC=C3F)Cl |
Product Overview
2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine (CAS 355821-33-9), with molecular formula C14H14ClFN4 and molecular weight 292.09 g/mol. IUPAC: 2-chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine.
Chemical Property Profile of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine
Property Insights of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine
The XLogP value of 2.5957 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine. With a topological polar surface area (TPSA) of 32.26 Ų, 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine?
The CAS number of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine is 355821-33-9.
What is the molecular formula of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine?
The molecular formula of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine is C14H14ClFN4.
What is the molecular weight of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine?
The molecular weight of 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine is 292.09 g/mol.
Where can I buy 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine?
You can request a quote for 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-5-fluoro-4-(4-phenylpiperazin-1-yl)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.