![2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol structure](/static/products/355/355434-80-9.png)
2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol
TL;DR: 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol (CAS 355434-80-9) is a chemical compound with molecular formula C20H18FN3O2S and molecular weight 383.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[5-(4-fluorophenyl)furan-2-yl]-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7)-dien-3-one
Also Known As: 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol, 2-[5-(4-fluorophenyl)furan-2-yl]-7-methyl-2,3,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(1H)-one, 2-(5-(4-fluorophenyl)furan-2-yl)-7-methyl-2,3,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(1H)-one, 2-[5-(4-fluorophenyl)(2-furyl)]-7-methyl-1,2,3,5,6,7,8-heptahydropyrimidino[5' ,4'-4,5]thiopheno[2,3-c]pyridin-4-one, 5-[5-(4-fluorophenyl)furan-2-yl]-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7)-dien-3-one
| Molecular Formula | C20H18FN3O2S |
|---|---|
| Molecular Weight | 383.11 g/mol |
| LogP | 3.9892 |
| Topological Polar Surface Area | 57.51 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 383.11038 |
| Heavy Atoms | 27 |
| Complexity | 1024.5289 |
Chemical Identifiers
| CAS Number | 355434-80-9 |
|---|---|
| SMILES | CN1CCC2=C(C1)SC3=C2C(=O)NC(N3)C4=CC=C(O4)C5=CC=C(C=C5)F |
Product Overview
2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol (CAS 355434-80-9), with molecular formula C20H18FN3O2S and molecular weight 383.11 g/mol. IUPAC: 5-[5-(4-fluorophenyl)furan-2-yl]-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7)-dien-3-one.
Chemical Property Profile of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol
Property Insights of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol
The XLogP value of 3.9892 indicates that 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.51 Ų, 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol?
The CAS number of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol is 355434-80-9.
What is the molecular formula of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol?
The molecular formula of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol is C20H18FN3O2S.
What is the molecular weight of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol?
The molecular weight of 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol is 383.11 g/mol.
Where can I buy 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol?
You can request a quote for 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 2-[5-(4-fluorophenyl)-2-furyl]-7-methyl-1,2,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.