1,4-Bis(3-chlorobenzyl)piperazine
TL;DR: 1,4-Bis(3-chlorobenzyl)piperazine (CAS 355396-54-2) is a chemical compound with molecular formula C18H20Cl2N2 and molecular weight 334.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1,4-bis[(3-chlorophenyl)methyl]piperazine
Also Known As: Trazodone impurity 50, 1,4-bis(3-chlorobenzyl)piperazine, 1,4-bis[(3-chlorophenyl)methyl]piperazine, Trazodone Hydrochloride Impurity 27, BAS 01840588
| Molecular Formula | C18H20Cl2N2 |
|---|---|
| Molecular Weight | 334.10 g/mol |
| LogP | 4.3112 |
| Topological Polar Surface Area | 6.48 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 334.10034 |
| Heavy Atoms | 22 |
| Complexity | 566.48914 |
Chemical Identifiers
| CAS Number | 355396-54-2 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC(=CC=C2)Cl)CC3=CC(=CC=C3)Cl |
Product Overview
1,4-Bis(3-chlorobenzyl)piperazine (CAS 355396-54-2), with molecular formula C18H20Cl2N2 and molecular weight 334.10 g/mol. IUPAC: 1,4-bis[(3-chlorophenyl)methyl]piperazine.
Chemical Property Profile of 1,4-Bis(3-chlorobenzyl)piperazine
Property Insights of 1,4-Bis(3-chlorobenzyl)piperazine
The XLogP value of 4.3112 indicates that 1,4-Bis(3-chlorobenzyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.48 Ų, 1,4-Bis(3-chlorobenzyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,4-Bis(3-chlorobenzyl)piperazine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,4-Bis(3-chlorobenzyl)piperazine?
The CAS number of 1,4-Bis(3-chlorobenzyl)piperazine is 355396-54-2.
What is the molecular formula of 1,4-Bis(3-chlorobenzyl)piperazine?
The molecular formula of 1,4-Bis(3-chlorobenzyl)piperazine is C18H20Cl2N2.
What is the molecular weight of 1,4-Bis(3-chlorobenzyl)piperazine?
The molecular weight of 1,4-Bis(3-chlorobenzyl)piperazine is 334.10 g/mol.
Where can I buy 1,4-Bis(3-chlorobenzyl)piperazine?
You can request a quote for 1,4-Bis(3-chlorobenzyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,4-Bis(3-chlorobenzyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1,4-Bis(3-chlorobenzyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.