methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate
TL;DR: methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate (CAS 355147-25-0) is a chemical compound with molecular formula C16H14F3NO4S and molecular weight 373.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 3,3,3-trifluoro-2-hydroxy-2-[3-methyl-4-(thiophene-2-carbonylamino)phenyl]propanoate
Also Known As: methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate, methyl 3,3,3-trifluoro-2-hydroxy-2-[3-methyl-4-(2-thienylcarbonylamino)phenyl] propanoate, 3,3,3-Trifluoro-2-hydroxy-2-{3-methyl-4-[(thiophene-2-carbonyl)-amino]-phenyl}-propionic acid methyl ester, methyl 3,3,3-trifluoro-2-hydroxy-2-[3-methyl-4-(thiophene-2-carbonylamino)phenyl]propanoate, methyl 3,3,3-trifluoro-2-hydroxy-2-{3-methyl-4-[(thiophen-2-ylcarbonyl)amino]phenyl}propanoate
| Molecular Formula | C16H14F3NO4S |
|---|---|
| Molecular Weight | 373.06 g/mol |
| LogP | 3.23172 |
| Topological Polar Surface Area | 75.63 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 373.05957 |
| Heavy Atoms | 25 |
| Complexity | 789.17267 |
Chemical Identifiers
| CAS Number | 355147-25-0 |
|---|---|
| SMILES | CC1=C(C=CC(=C1)C(C(=O)OC)(C(F)(F)F)O)NC(=O)C2=CC=CS2 |
Product Overview
methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate (CAS 355147-25-0), with molecular formula C16H14F3NO4S and molecular weight 373.06 g/mol. IUPAC: methyl 3,3,3-trifluoro-2-hydroxy-2-[3-methyl-4-(thiophene-2-carbonylamino)phenyl]propanoate.
Chemical Property Profile of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate
Property Insights of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate
The XLogP value of 3.23172 indicates that methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.63 Ų falls within the moderate polarity range, balancing permeability and solubility for methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate. Following Lipinski's Rule of Five, methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate?
The CAS number of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate is 355147-25-0.
What is the molecular formula of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate?
The molecular formula of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate is C16H14F3NO4S.
What is the molecular weight of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate?
The molecular weight of methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate is 373.06 g/mol.
Where can I buy methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate?
You can request a quote for methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate?
Yes, KEHONG BIO provides custom synthesis services for methyl 3,3,3-trifluoro-2-hydroxy-2-(3-methyl-4-(thiophene-2-carboxamido)phenyl)propanoate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.