(E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide structure

(E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide

TL;DR: (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide (CAS 354774-84-8) is a chemical compound with molecular formula C19H16ClFN4O4S and molecular weight 450.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(E)-[4-(2-chloro-5-fluoropyrimidin-4-yl)oxy-3-methoxyphenyl]methylideneamino]-4-methylbenzenesulfonamide

Also Known As: (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide, N'-[(E)-{4-[(2-chloro-5-fluoropyrimidin-4-yl)oxy]-3-methoxyphenyl}methylidene]-4-methylbenzenesulfonohydrazide, N-[(E)-[4-(2-chloro-5-fluoropyrimidin-4-yl)oxy-3-methoxyphenyl]methylideneamino]-4-methylbenzenesulfonamide

CAS: 354774-84-8
Molecular Formula C19H16ClFN4O4S
Molecular Weight 450.06 g/mol
LogP 3.69082
Topological Polar Surface Area 102.77 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 7
Exact Mass 450.0565
Heavy Atoms 30
Complexity 1187.6388

Chemical Identifiers

CAS Number 354774-84-8
SMILES CC1=CC=C(C=C1)S(=O)(=O)N/N=C/C2=CC(=C(C=C2)OC3=NC(=NC=C3F)Cl)OC

Product Overview

(E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide (CAS 354774-84-8), with molecular formula C19H16ClFN4O4S and molecular weight 450.06 g/mol. IUPAC: N-[(E)-[4-(2-chloro-5-fluoropyrimidin-4-yl)oxy-3-methoxyphenyl]methylideneamino]-4-methylbenzenesulfonamide.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide

XLogP
3.69082
TPSA (Topological Polar Surface Area)
102.77
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
7
Heavy Atoms
30
Complexity
1187.6388
Exact Mass
450.0565
Monoisotopic Mass
450.0565
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide

The XLogP value of 3.69082 indicates that (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.77 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide. Following Lipinski's Rule of Five, (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide?

The CAS number of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide is 354774-84-8.

What is the molecular formula of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide?

The molecular formula of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide is C19H16ClFN4O4S.

What is the molecular weight of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide?

The molecular weight of (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide is 450.06 g/mol.

Where can I buy (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide?

You can request a quote for (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(4-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?