N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide
TL;DR: N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide (CAS 354772-78-4) is a chemical compound with molecular formula C12H11F7N2O and molecular weight 332.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[1,1,1,3,3,3-hexafluoro-2-(2-fluoroanilino)propan-2-yl]propanamide
Also Known As: NCI60_025593, N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide, N-{1,1,1,3,3,3-hexafluoro-2-[(2-fluorophenyl)amino]propan-2-yl}propanamide, N-[1,1,1,3,3,3-hexafluoro-2-(2-fluoroanilino)propan-2-yl]propanamide, N-(1,1,1,3,3,3-hexafluoro-2-((2-fluorophenyl)amino)propan-2-yl)propionamide
| Molecular Formula | C12H11F7N2O |
|---|---|
| Molecular Weight | 332.08 g/mol |
| LogP | 4.6 |
| Topological Polar Surface Area | 41.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 332.07596 |
| Heavy Atoms | 22 |
| Complexity | 380.0 |
Chemical Identifiers
| CAS Number | 354772-78-4 |
|---|---|
| SMILES | CCC(=O)NC(C(F)(F)F)(C(F)(F)F)NC1=CC=CC=C1F |
| InChIKey | UOKORTHVNULANK-UHFFFAOYSA-N |
Product Overview
N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide (CAS 354772-78-4), with molecular formula C12H11F7N2O and molecular weight 332.08 g/mol. IUPAC: N-[1,1,1,3,3,3-hexafluoro-2-(2-fluoroanilino)propan-2-yl]propanamide.
Chemical Property Profile of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide
Property Insights of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide
The XLogP value of 4.6 indicates that N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.1 Ų, N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide?
The CAS number of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide is 354772-78-4.
What is the molecular formula of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide?
The molecular formula of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide is C12H11F7N2O.
What is the molecular weight of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide?
The molecular weight of N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide is 332.08 g/mol.
Where can I buy N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide?
You can request a quote for N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2,2,2-Trifluoro-1-(2-fluoroanilino)-1-(trifluoromethyl)ethyl)propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.