AL-281/36997030 structure

AL-281/36997030

TL;DR: AL-281/36997030 (CAS 354551-57-8) is a chemical compound with molecular formula C25H23ClN2O2S and molecular weight 450.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl-3-methylspiro[6H-benzo[h]quinazoline-5,1'-cyclopentane]-4-one

Also Known As: AL-281/36997030, 2-[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl-3-methylspiro[6H-benzo[h]quinazoline-5,1'-cyclopentane]-4-one, 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-methyl-5,6-dihydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)-4(3H)-one, 2-((2-(4-chlorophenyl)-2-oxoethyl)thio)-3-methyl-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one, 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-3-methyl-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one

CAS: 354551-57-8
Molecular Formula C25H23ClN2O2S
Molecular Weight 450.12 g/mol
LogP 5.4436
Topological Polar Surface Area 51.96 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 450.11688
Heavy Atoms 31
Complexity 1227.2596

Chemical Identifiers

CAS Number 354551-57-8
SMILES CN1C(=O)C2=C(C3=CC=CC=C3CC24CCCC4)N=C1SCC(=O)C5=CC=C(C=C5)Cl

Product Overview

AL-281/36997030 (CAS 354551-57-8), with molecular formula C25H23ClN2O2S and molecular weight 450.12 g/mol. IUPAC: 2-[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl-3-methylspiro[6H-benzo[h]quinazoline-5,1'-cyclopentane]-4-one.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AL-281/36997030

XLogP
5.4436
TPSA (Topological Polar Surface Area)
51.96
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
31
Complexity
1227.2596
Exact Mass
450.11688
Monoisotopic Mass
450.11688
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AL-281/36997030

The XLogP value of 5.4436 indicates that AL-281/36997030 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.96 Ų, AL-281/36997030 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AL-281/36997030 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AL-281/36997030?

The CAS number of AL-281/36997030 is 354551-57-8.

What is the molecular formula of AL-281/36997030?

The molecular formula of AL-281/36997030 is C25H23ClN2O2S.

What is the molecular weight of AL-281/36997030?

The molecular weight of AL-281/36997030 is 450.12 g/mol.

Where can I buy AL-281/36997030?

You can request a quote for AL-281/36997030 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AL-281/36997030?

Yes, KEHONG BIO provides custom synthesis services for AL-281/36997030 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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