2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide
TL;DR: 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide (CAS 354551-31-8) is a chemical compound with molecular formula C11H10ClN3OS and molecular weight 267.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
Also Known As: 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide, 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)pyridine-3-carboxamide, 2-chloro-N-(dimethyl-1,3-thiazol-2-yl)pyridine-3-carboxamide, 2-CHLORO-N~3~-(4,5-DIMETHYL-1,3-THIAZOL-2-YL)NICOTINAMIDE
| Molecular Formula | C11H10ClN3OS |
|---|---|
| Molecular Weight | 267.02 g/mol |
| LogP | 3.06064 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 267.02332 |
| Heavy Atoms | 17 |
| Complexity | 548.09424 |
Chemical Identifiers
| CAS Number | 354551-31-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)C2=C(N=CC=C2)Cl)C |
Product Overview
2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide (CAS 354551-31-8), with molecular formula C11H10ClN3OS and molecular weight 267.02 g/mol. IUPAC: 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)pyridine-3-carboxamide.
Chemical Property Profile of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide
Property Insights of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide
The XLogP value of 3.06064 indicates that 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide?
The CAS number of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide is 354551-31-8.
What is the molecular formula of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide?
The molecular formula of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide is C11H10ClN3OS.
What is the molecular weight of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide?
The molecular weight of 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide is 267.02 g/mol.
Where can I buy 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide?
You can request a quote for 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.