(Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one
TL;DR: (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one (CAS 354545-77-0) is a chemical compound with molecular formula C15H11NOS2 and molecular weight 285.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(3-methylthiophen-2-yl)methylidene]-2-phenyl-1,3-thiazol-4-one
Also Known As: (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one, F0921-2867, (5Z)-5-[(3-methylthiophen-2-yl)methylidene]-2-phenyl-1,3-thiazol-4-one, (5Z)-5-[(3-methylthiophen-2-yl)methylidene]-2-phenyl-4,5-dihydro-1,3-thiazol-4-one, 5-((3-Methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one
| Molecular Formula | C15H11NOS2 |
|---|---|
| Molecular Weight | 285.03 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 83.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.0282 |
| Heavy Atoms | 19 |
| Complexity | 424.0 |
Chemical Identifiers
| CAS Number | 354545-77-0 |
|---|---|
| SMILES | CC1=C(SC=C1)/C=C\2/C(=O)N=C(S2)C3=CC=CC=C3 |
| InChIKey | CWOWHCIZQPCWFS-LCYFTJDESA-N |
Product Overview
(Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one (CAS 354545-77-0), with molecular formula C15H11NOS2 and molecular weight 285.03 g/mol. IUPAC: (5Z)-5-[(3-methylthiophen-2-yl)methylidene]-2-phenyl-1,3-thiazol-4-one.
Chemical Property Profile of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one
Property Insights of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one
The XLogP value of 4.2 indicates that (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one. Following Lipinski's Rule of Five, (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one?
The CAS number of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one is 354545-77-0.
What is the molecular formula of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one?
The molecular formula of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one is C15H11NOS2.
What is the molecular weight of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one?
The molecular weight of (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one is 285.03 g/mol.
Where can I buy (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one?
You can request a quote for (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-5-((3-methylthiophen-2-yl)methylene)-2-phenylthiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.