7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol
TL;DR: 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol (CAS 354538-69-5) is a chemical compound with molecular formula C18H13ClN2OS2 and molecular weight 372.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-1H-quinolin-2-one
Also Known As: ChemDiv3_001854, IDI1_020820, BRD-K86762382-001-01-3, 7-chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol, 7-chloro-3-((4,5-dihydrothiazol-2-yl)thio)-4-phenylquinolin-2-ol
| Molecular Formula | C18H13ClN2OS2 |
|---|---|
| Molecular Weight | 372.02 g/mol |
| LogP | 5.0434 |
| Topological Polar Surface Area | 45.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 372.01578 |
| Heavy Atoms | 24 |
| Complexity | 999.0665 |
Chemical Identifiers
| CAS Number | 354538-69-5 |
|---|---|
| SMILES | C1CSC(=N1)SC2=C(C3=C(C=C(C=C3)Cl)NC2=O)C4=CC=CC=C4 |
Product Overview
7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol (CAS 354538-69-5), with molecular formula C18H13ClN2OS2 and molecular weight 372.02 g/mol. IUPAC: 7-chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-1H-quinolin-2-one.
Chemical Property Profile of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol
Property Insights of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol
The XLogP value of 5.0434 indicates that 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.22 Ų, 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol?
The CAS number of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol is 354538-69-5.
What is the molecular formula of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol?
The molecular formula of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol is C18H13ClN2OS2.
What is the molecular weight of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol?
The molecular weight of 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol is 372.02 g/mol.
Where can I buy 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol?
You can request a quote for 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol?
Yes, KEHONG BIO provides custom synthesis services for 7-Chloro-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)-4-phenyl-2-quinolinol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.