2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide
TL;DR: 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide (CAS 354536-79-1) is a chemical compound with molecular formula C22H13BrClFN2O and molecular weight 453.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)quinoline-4-carboxamide
Also Known As: 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide, 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)quinoline-4-carboxamide, 2-(4-BROMOPHENYL)-N~4~-(4-CHLORO-2-FLUOROPHENYL)-4-QUINOLINECARBOXAMIDE
| Molecular Formula | C22H13BrClFN2O |
|---|---|
| Molecular Weight | 453.99 g/mol |
| LogP | 6.7091 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 453.98837 |
| Heavy Atoms | 28 |
| Complexity | 1195.0043 |
Chemical Identifiers
| CAS Number | 354536-79-1 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=C(C=C3)Br)C(=O)NC4=C(C=C(C=C4)Cl)F |
Product Overview
2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide (CAS 354536-79-1), with molecular formula C22H13BrClFN2O and molecular weight 453.99 g/mol. IUPAC: 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)quinoline-4-carboxamide.
Chemical Property Profile of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide
Property Insights of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide
The XLogP value of 6.7091 indicates that 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide?
The CAS number of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide is 354536-79-1.
What is the molecular formula of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide?
The molecular formula of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide is C22H13BrClFN2O.
What is the molecular weight of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide?
The molecular weight of 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide is 453.99 g/mol.
Where can I buy 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide?
You can request a quote for 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-bromophenyl)-N-(4-chloro-2-fluorophenyl)-4-quinolinecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.