Chloroquine Hydrochloride structure

Chloroquine Hydrochloride

TL;DR: Chloroquine Hydrochloride (CAS 3545-67-3) is a chemical compound with molecular formula C18H28Cl3N3 and molecular weight 391.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;dihydrochloride

Also Known As: Chloroquine hydrochloride, Chloroquine HCl, Chloroquine dihydrochloride, Aralen hydrochloride, Aralen HCl

CAS: 3545-67-3
Molecular Formula C18H28Cl3N3
Molecular Weight 391.13 g/mol
LogP 5.65
Topological Polar Surface Area 28.2 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 3
Rotatable Bonds 8
Exact Mass 391.1349
Heavy Atoms 24
Complexity 309.0

Chemical Identifiers

CAS Number 3545-67-3
SMILES CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.Cl.Cl
InChIKey PCFGECQRSMVKCC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (2 patents)

Product Overview

Chloroquine Hydrochloride (CAS 3545-67-3), with molecular formula C18H28Cl3N3 and molecular weight 391.13 g/mol. IUPAC: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Chloroquine Hydrochloride

XLogP
5.65
TPSA (Topological Polar Surface Area)
28.2
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
3
Rotatable Bonds
8
Heavy Atoms
24
Complexity
309.0
Exact Mass
391.1349
Monoisotopic Mass
391.1349
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Chloroquine Hydrochloride

The XLogP value of 5.65 indicates that Chloroquine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.2 Ų, Chloroquine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Chloroquine Hydrochloride has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Chloroquine Hydrochloride?

The CAS number of Chloroquine Hydrochloride is 3545-67-3.

What is the molecular formula of Chloroquine Hydrochloride?

The molecular formula of Chloroquine Hydrochloride is C18H28Cl3N3.

What is the molecular weight of Chloroquine Hydrochloride?

The molecular weight of Chloroquine Hydrochloride is 391.13 g/mol.

Where can I buy Chloroquine Hydrochloride?

You can request a quote for Chloroquine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Chloroquine Hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Chloroquine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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