Bendamustine Hydrochloride
TL;DR: Bendamustine Hydrochloride (CAS 3543-75-7) is a chemical compound with molecular formula C16H22Cl3N3O2 and molecular weight 393.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride
Also Known As: Bendamustine hydrochloride, Bendamustine HCl, Treanda, Ribomustin, Cytostasan
| Molecular Formula | C16H22Cl3N3O2 |
|---|---|
| Molecular Weight | 393.08 g/mol |
| LogP | 3.69 |
| Topological Polar Surface Area | 58.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 9 |
| Exact Mass | 393.07776 |
| Heavy Atoms | 24 |
| Complexity | 380.0 |
Chemical Identifiers
| CAS Number | 3543-75-7 |
|---|---|
| SMILES | CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl |
| InChIKey | ZHSKUOZOLHMKEA-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Bendamustine Hydrochloride (CAS 3543-75-7), with molecular formula C16H22Cl3N3O2 and molecular weight 393.08 g/mol. IUPAC: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride.
Chemical Property Profile of Bendamustine Hydrochloride
Property Insights of Bendamustine Hydrochloride
The XLogP value of 3.69 indicates that Bendamustine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.4 Ų, Bendamustine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bendamustine Hydrochloride has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bendamustine Hydrochloride?
The CAS number of Bendamustine Hydrochloride is 3543-75-7.
What is the molecular formula of Bendamustine Hydrochloride?
The molecular formula of Bendamustine Hydrochloride is C16H22Cl3N3O2.
What is the molecular weight of Bendamustine Hydrochloride?
The molecular weight of Bendamustine Hydrochloride is 393.08 g/mol.
Where can I buy Bendamustine Hydrochloride?
You can request a quote for Bendamustine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bendamustine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Bendamustine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.