氯二氟乙酰氯
TL;DR: 氯二氟乙酰氯 (CAS 354-24-5) is a chemical compound with molecular formula C2Cl2F2O and molecular weight 147.93 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氯二氟乙酰氯
2-chloro-2,2-difluoroacetyl chloride
Also Known As: Chlorodifluoroacetyl chloride, chloro(difluoro)acetyl chloride, 2-chloro-2,2-difluoroacetyl chloride, Chlorodifluoroacetylchloride, Acetyl chloride, chlorodifluoro-
| Molecular Formula | C2Cl2F2O |
|---|---|
| Molecular Weight | 147.93 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 17.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 147.92943 |
| Heavy Atoms | 7 |
| Complexity | 91.0 |
Chemical Identifiers
| CAS Number | 354-24-5 |
|---|---|
| SMILES | C(=O)(C(F)(F)Cl)Cl |
| InChIKey | AZPWOLJQERBBBM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
氯二氟乙酰氯 (CAS 354-24-5), with molecular formula C2Cl2F2O and molecular weight 147.93 g/mol. IUPAC: 2-chloro-2,2-difluoroacetyl chloride.
Chemical Property Profile of 氯二氟乙酰氯
Property Insights of 氯二氟乙酰氯
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 氯二氟乙酰氯. With a topological polar surface area (TPSA) of 17.1 Ų, 氯二氟乙酰氯 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 氯二氟乙酰氯 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氯二氟乙酰氯?
The CAS number of 氯二氟乙酰氯 is 354-24-5.
What is the molecular formula of 氯二氟乙酰氯?
The molecular formula of 氯二氟乙酰氯 is C2Cl2F2O.
What is the molecular weight of 氯二氟乙酰氯?
The molecular weight of 氯二氟乙酰氯 is 147.93 g/mol.
Where can I buy 氯二氟乙酰氯?
You can request a quote for 氯二氟乙酰氯 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氯二氟乙酰氯?
Yes, KEHONG BIO provides custom synthesis services for 氯二氟乙酰氯 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.