Amphotericin b methyl ester hydrochloride
TL;DR: Amphotericin b methyl ester hydrochloride (CAS 35375-29-2) is a chemical compound with molecular formula C48H76ClNO17 and molecular weight 973.48 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate;hydrochloride
Also Known As: amphotericin b methyl ester hydrochloride
| Molecular Formula | C48H76ClNO17 |
|---|---|
| Molecular Weight | 973.48 g/mol |
| LogP | 1.2219 |
| Topological Polar Surface Area | 309.0 Ų |
| Hydrogen Bond Donors | 12 |
| Hydrogen Bond Acceptors | 18 |
| Rotatable Bonds | 4 |
| Exact Mass | 973.48016 |
| Heavy Atoms | 67 |
| Complexity | 1680.0 |
Chemical Identifiers
| CAS Number | 35375-29-2 |
|---|---|
| SMILES | C[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)OC)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O.Cl |
| InChIKey | FCUABMXRRQIKMV-ZZAPUJMKSA-N |
Product Overview
Amphotericin b methyl ester hydrochloride (CAS 35375-29-2), with molecular formula C48H76ClNO17 and molecular weight 973.48 g/mol. IUPAC: methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate;hydrochloride.
Chemical Property Profile of Amphotericin b methyl ester hydrochloride
Property Insights of Amphotericin b methyl ester hydrochloride
The XLogP value of 1.2219 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Amphotericin b methyl ester hydrochloride. The TPSA of 309.0 Ų indicates high polarity, suggesting Amphotericin b methyl ester hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amphotericin b methyl ester hydrochloride has 12 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amphotericin b methyl ester hydrochloride?
The CAS number of Amphotericin b methyl ester hydrochloride is 35375-29-2.
What is the molecular formula of Amphotericin b methyl ester hydrochloride?
The molecular formula of Amphotericin b methyl ester hydrochloride is C48H76ClNO17.
What is the molecular weight of Amphotericin b methyl ester hydrochloride?
The molecular weight of Amphotericin b methyl ester hydrochloride is 973.48 g/mol.
Where can I buy Amphotericin b methyl ester hydrochloride?
You can request a quote for Amphotericin b methyl ester hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amphotericin b methyl ester hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Amphotericin b methyl ester hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.