(4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone
TL;DR: (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone (CAS 353248-03-0) is a chemical compound with molecular formula C26H23ClN4O and molecular weight 442.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(6-chloro-4-phenylquinazolin-2-yl)piperazin-1-yl]-(4-methylphenyl)methanone
Also Known As: BAS 01052675, (4-(6-chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone, [4-(6-chloro-4-phenylquinazolin-2-yl)piperazin-1-yl]-(4-methylphenyl)methanone, 6-CHLORO-2-[4-(4-METHYLBENZOYL)PIPERAZIN-1-YL]-4-PHENYLQUINAZOLINE, F1590-0183
| Molecular Formula | C26H23ClN4O |
|---|---|
| Molecular Weight | 442.16 g/mol |
| LogP | 5.22102 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 442.15604 |
| Heavy Atoms | 32 |
| Complexity | 1266.5074 |
Chemical Identifiers
| CAS Number | 353248-03-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C(=O)N2CCN(CC2)C3=NC4=C(C=C(C=C4)Cl)C(=N3)C5=CC=CC=C5 |
Product Overview
(4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone (CAS 353248-03-0), with molecular formula C26H23ClN4O and molecular weight 442.16 g/mol. IUPAC: [4-(6-chloro-4-phenylquinazolin-2-yl)piperazin-1-yl]-(4-methylphenyl)methanone.
Chemical Property Profile of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone
Property Insights of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone
The XLogP value of 5.22102 indicates that (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.33 Ų, (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone?
The CAS number of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone is 353248-03-0.
What is the molecular formula of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone?
The molecular formula of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone is C26H23ClN4O.
What is the molecular weight of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone?
The molecular weight of (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone is 442.16 g/mol.
Where can I buy (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone?
You can request a quote for (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl)(p-tolyl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.