Fmoc-O-tert-butyl-L-beta-homothreonine
TL;DR: Fmoc-O-tert-butyl-L-beta-homothreonine (CAS 353245-99-5) is a chemical compound with molecular formula C24H29NO5 and molecular weight 411.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,4R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[(2-methylpropan-2-yl)oxy]pentanoic acid
Also Known As: Fmoc-L-beta-homothreonine(OtBu), Fmoc-, A-HomoThr(tBu)-OH, Fmoc-O-tert-butyl-L-beta-homothreonine, Fmoc-beta-Homothr(tBu)-OH
| Molecular Formula | C24H29NO5 |
|---|---|
| Molecular Weight | 411.20 g/mol |
| LogP | 4.572 |
| Topological Polar Surface Area | 84.86 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 411.20456 |
| Heavy Atoms | 30 |
| Complexity | 872.30743 |
Chemical Identifiers
| CAS Number | 353245-99-5 |
|---|---|
| SMILES | C[C@H]([C@@H](CC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OC(C)(C)C |
Product Overview
Fmoc-O-tert-butyl-L-beta-homothreonine (CAS 353245-99-5), with molecular formula C24H29NO5 and molecular weight 411.20 g/mol. IUPAC: (3R,4R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[(2-methylpropan-2-yl)oxy]pentanoic acid.
Chemical Property Profile of Fmoc-O-tert-butyl-L-beta-homothreonine
Property Insights of Fmoc-O-tert-butyl-L-beta-homothreonine
The XLogP value of 4.572 indicates that Fmoc-O-tert-butyl-L-beta-homothreonine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.86 Ų falls within the moderate polarity range, balancing permeability and solubility for Fmoc-O-tert-butyl-L-beta-homothreonine. Following Lipinski's Rule of Five, Fmoc-O-tert-butyl-L-beta-homothreonine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fmoc-O-tert-butyl-L-beta-homothreonine?
The CAS number of Fmoc-O-tert-butyl-L-beta-homothreonine is 353245-99-5.
What is the molecular formula of Fmoc-O-tert-butyl-L-beta-homothreonine?
The molecular formula of Fmoc-O-tert-butyl-L-beta-homothreonine is C24H29NO5.
What is the molecular weight of Fmoc-O-tert-butyl-L-beta-homothreonine?
The molecular weight of Fmoc-O-tert-butyl-L-beta-homothreonine is 411.20 g/mol.
Where can I buy Fmoc-O-tert-butyl-L-beta-homothreonine?
You can request a quote for Fmoc-O-tert-butyl-L-beta-homothreonine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fmoc-O-tert-butyl-L-beta-homothreonine?
Yes, KEHONG BIO provides custom synthesis services for Fmoc-O-tert-butyl-L-beta-homothreonine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.