HPT 861
TL;DR: HPT 861 (CAS 3528-72-1) is a chemical compound with molecular formula C18H21Cl2N3O and molecular weight 365.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-1-[2-(dimethylamino)ethyl]-2-phenyl-2,3-dihydroquinazolin-4-one;hydrochloride
Also Known As: HPT 861, 7-Chloro-2,3-dihydro-1-(2-(dimethylamino)ethyl)-2-phenyl-4(1H)-quinazolinone hydrochloride, 4(1H)-Quinazolinone, 2,3-dihydro-7-chloro-1-(2-(dimethylamino)ethyl)-2-phenyl-, hydrochloride, 7-chloro-1-(2-dimethylaminoethyl)-2-phenyl-2,3-dihydroquinazolin-4-onehydrochloride, 7-Chloro-1-[2-(dimethylamino)ethyl]-2-phenyl-2,3-dihydro-4(1H)-quinazolinone hydrochloride
| Molecular Formula | C18H21Cl2N3O |
|---|---|
| Molecular Weight | 365.11 g/mol |
| LogP | 3.57 |
| Topological Polar Surface Area | 35.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 365.10617 |
| Heavy Atoms | 24 |
| Complexity | 411.0 |
Chemical Identifiers
| CAS Number | 3528-72-1 |
|---|---|
| SMILES | CN(C)CCN1C(NC(=O)C2=C1C=C(C=C2)Cl)C3=CC=CC=C3.Cl |
| InChIKey | NWISGBZOZYFCPS-UHFFFAOYSA-N |
Product Overview
HPT 861 (CAS 3528-72-1), with molecular formula C18H21Cl2N3O and molecular weight 365.11 g/mol. IUPAC: 7-chloro-1-[2-(dimethylamino)ethyl]-2-phenyl-2,3-dihydroquinazolin-4-one;hydrochloride.
Chemical Property Profile of HPT 861
Property Insights of HPT 861
The XLogP value of 3.57 indicates that HPT 861 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.6 Ų, HPT 861 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, HPT 861 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of HPT 861?
The CAS number of HPT 861 is 3528-72-1.
What is the molecular formula of HPT 861?
The molecular formula of HPT 861 is C18H21Cl2N3O.
What is the molecular weight of HPT 861?
The molecular weight of HPT 861 is 365.11 g/mol.
Where can I buy HPT 861?
You can request a quote for HPT 861 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for HPT 861?
Yes, KEHONG BIO provides custom synthesis services for HPT 861 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.