![(Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate structure](/static/products/352/352663-03-7.png)
(Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate
TL;DR: (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate (CAS 352663-03-7) is a chemical compound with molecular formula C23H13Cl2F2N3O3S and molecular weight 519.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl (2Z)-5-amino-7-(2-chloro-6-fluorophenyl)-2-[(2-chloro-6-fluorophenyl)methylidene]-6-cyano-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-8-carboxylate
Also Known As: (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate, methyl (2Z)-5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-8-carboxylate, methyl (2Z)-5-amino-7-(2-chloro-6-fluorophenyl)-2-[(2-chloro-6-fluorophenyl)methylidene]-6-cyano-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-8-carboxylate
| Molecular Formula | C23H13Cl2F2N3O3S |
|---|---|
| Molecular Weight | 519.00 g/mol |
| LogP | 3.09558 |
| Topological Polar Surface Area | 98.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 519.00226 |
| Heavy Atoms | 34 |
| Complexity | 1578.9653 |
Chemical Identifiers
| CAS Number | 352663-03-7 |
|---|---|
| SMILES | COC(=O)C1=C2N(C(=C(C1C3=C(C=CC=C3Cl)F)C#N)N)C(=O)/C(=C/C4=C(C=CC=C4Cl)F)/S2 |
Product Overview
(Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate (CAS 352663-03-7), with molecular formula C23H13Cl2F2N3O3S and molecular weight 519.00 g/mol. IUPAC: methyl (2Z)-5-amino-7-(2-chloro-6-fluorophenyl)-2-[(2-chloro-6-fluorophenyl)methylidene]-6-cyano-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-8-carboxylate.
Chemical Property Profile of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate
Property Insights of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate
The XLogP value of 3.09558 indicates that (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 98.11 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate. Following Lipinski's Rule of Five, (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate?
The CAS number of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate is 352663-03-7.
What is the molecular formula of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate?
The molecular formula of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate is C23H13Cl2F2N3O3S.
What is the molecular weight of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate?
The molecular weight of (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate is 519.00 g/mol.
Where can I buy (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate?
You can request a quote for (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (Z)-methyl 5-amino-2-(2-chloro-6-fluorobenzylidene)-7-(2-chloro-6-fluorophenyl)-6-cyano-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-8-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.