![8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione structure](/static/products/3524/352444-12-3.webp)
8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione
TL;DR: 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione (CAS 352444-12-3) is a chemical compound with molecular formula C22H32N2O2S and molecular weight 388.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione
Also Known As: 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione, 8a'-hydroxy-1'-(4-methoxyphenethyl)hexahydro-1'H-spiro[cyclohexane-1,4'-quinazoline]-2'(3'H)-thione, 8a'-hydroxy-1'-[2-(4-methoxyphenyl)ethyl]hexahydro-1'H-spiro[cyclohexane-1,4'-quinazoline]-2'(3'H)-thione
| Molecular Formula | C22H32N2O2S |
|---|---|
| Molecular Weight | 388.22 g/mol |
| LogP | 4.0095 |
| Topological Polar Surface Area | 44.73 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 388.21844 |
| Heavy Atoms | 27 |
| Complexity | 671.39526 |
Chemical Identifiers
| CAS Number | 352444-12-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)CCN2C(=S)NC3(CCCCC3)C4C2(CCCC4)O |
Product Overview
8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione (CAS 352444-12-3), with molecular formula C22H32N2O2S and molecular weight 388.22 g/mol. IUPAC: 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione.
Chemical Property Profile of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione
Property Insights of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione
The XLogP value of 4.0095 indicates that 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.73 Ų, 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione?
The CAS number of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione is 352444-12-3.
What is the molecular formula of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione?
The molecular formula of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione is C22H32N2O2S.
What is the molecular weight of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione?
The molecular weight of 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione is 388.22 g/mol.
Where can I buy 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione?
You can request a quote for 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione?
Yes, KEHONG BIO provides custom synthesis services for 8a-hydroxy-1-[2-(4-methoxyphenyl)ethyl]spiro[3,4a,5,6,7,8-hexahydroquinazoline-4,1'-cyclohexane]-2-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.