![1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine structure](/static/products/3524/352436-52-3.webp)
1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine
TL;DR: 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine (CAS 352436-52-3) is a chemical compound with molecular formula C19H19F3N2O and molecular weight 348.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
phenyl-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone
Also Known As: BAS 01839957, 1-benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine, AB00098260-01, 1-benzoyl-4-[2-(trifluoromethyl)benzyl]piperazine, phenyl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone
| Molecular Formula | C19H19F3N2O |
|---|---|
| Molecular Weight | 348.14 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 23.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 348.14496 |
| Heavy Atoms | 25 |
| Complexity | 440.0 |
Chemical Identifiers
| CAS Number | 352436-52-3 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC=CC=C2C(F)(F)F)C(=O)C3=CC=CC=C3 |
| InChIKey | IKGGLYOQXBSLEE-UHFFFAOYSA-N |
Product Overview
1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine (CAS 352436-52-3), with molecular formula C19H19F3N2O and molecular weight 348.14 g/mol. IUPAC: phenyl-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone.
Chemical Property Profile of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine
Property Insights of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine
The XLogP value of 3.6 indicates that 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.6 Ų, 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine?
The CAS number of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine is 352436-52-3.
What is the molecular formula of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine?
The molecular formula of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine is C19H19F3N2O.
What is the molecular weight of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine?
The molecular weight of 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine is 348.14 g/mol.
Where can I buy 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine?
You can request a quote for 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-Benzoyl-4-{[2-(trifluoromethyl)phenyl]methyl}piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.