![(5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione structure](/static/products/352/352350-10-8.png)
(5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione
TL;DR: (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione (CAS 352350-10-8) is a chemical compound with molecular formula C22H20N4O3S and molecular weight 420.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-hydroxy-5-[2-(1H-indol-3-yl)ethyliminomethyl]-1-(2-methoxyphenyl)-2-sulfanylidenepyrimidin-4-one
Also Known As: (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione, (5E)-5-[[2-(1H-indol-3-yl)ethylamino]methylidene]-1-(2-methoxyphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione, (E)-5-(((2-(1H-indol-3-yl)ethyl)amino)methylene)-1-(2-methoxyphenyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, 5-({[2-(1H-indol-3-yl)ethyl]amino}methylene)-1-(2-methoxyphenyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione, 5-[[2-(1H-indol-3-yl)ethylamino]methylidene]-1-(2-methoxyphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione
| Molecular Formula | C22H20N4O3S |
|---|---|
| Molecular Weight | 420.13 g/mol |
| LogP | 3.75219 |
| Topological Polar Surface Area | 95.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 420.1256 |
| Heavy Atoms | 30 |
| Complexity | 1350.4993 |
Chemical Identifiers
| CAS Number | 352350-10-8 |
|---|---|
| SMILES | COC1=CC=CC=C1N2C(=C(C(=O)NC2=S)C=NCCC3=CNC4=CC=CC=C43)O |
Product Overview
(5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione (CAS 352350-10-8), with molecular formula C22H20N4O3S and molecular weight 420.13 g/mol. IUPAC: 6-hydroxy-5-[2-(1H-indol-3-yl)ethyliminomethyl]-1-(2-methoxyphenyl)-2-sulfanylidenepyrimidin-4-one.
Chemical Property Profile of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione
Property Insights of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione
The XLogP value of 3.75219 indicates that (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.4 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione. Following Lipinski's Rule of Five, (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione?
The CAS number of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione is 352350-10-8.
What is the molecular formula of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione?
The molecular formula of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione is C22H20N4O3S.
What is the molecular weight of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione?
The molecular weight of (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione is 420.13 g/mol.
Where can I buy (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione?
You can request a quote for (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-({[2-(1H-indol-3-yl)ethyl]amino}methylidene)-1-(2-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.