![2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide structure](/static/products/3522/352228-22-9.webp)
2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide
TL;DR: 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide (CAS 352228-22-9) is a chemical compound with molecular formula C14H10ClF3N2O and molecular weight 314.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]pyridine-3-carboxamide
Also Known As: 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide, AN-970/40920705, 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]pyridine-3-carboxamide, 2-Chloro-N-(2-methyl-3-(trifluoromethyl)phenyl)nicotinamide
| Molecular Formula | C14H10ClF3N2O |
|---|---|
| Molecular Weight | 314.04 g/mol |
| LogP | 4.31452 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 314.04337 |
| Heavy Atoms | 21 |
| Complexity | 686.1596 |
Chemical Identifiers
| CAS Number | 352228-22-9 |
|---|---|
| SMILES | CC1=C(C=CC=C1NC(=O)C2=C(N=CC=C2)Cl)C(F)(F)F |
Product Overview
2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide (CAS 352228-22-9), with molecular formula C14H10ClF3N2O and molecular weight 314.04 g/mol. IUPAC: 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]pyridine-3-carboxamide.
Chemical Property Profile of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide
Property Insights of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide
The XLogP value of 4.31452 indicates that 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide?
The CAS number of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide is 352228-22-9.
What is the molecular formula of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide?
The molecular formula of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide is C14H10ClF3N2O.
What is the molecular weight of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide?
The molecular weight of 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide is 314.04 g/mol.
Where can I buy 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide?
You can request a quote for 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-chloro-N-[2-methyl-3-(trifluoromethyl)phenyl]nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.