![Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate structure](/static/products/3519/351989-80-5.webp)
Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate
TL;DR: Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate (CAS 351989-80-5) is a chemical compound with molecular formula C17H14F3N3O2 and molecular weight 349.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
Also Known As: ETHYL 5-(P-TOLYL)-7-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLATE, ethyl 5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate, ETHYL5-(P-TOLYL)-7-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLATE
| Molecular Formula | C17H14F3N3O2 |
|---|---|
| Molecular Weight | 349.10 g/mol |
| LogP | 3.90022 |
| Topological Polar Surface Area | 56.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 349.10382 |
| Heavy Atoms | 25 |
| Complexity | 930.70135 |
Chemical Identifiers
| CAS Number | 351989-80-5 |
|---|---|
| SMILES | CCOC(=O)C1=C2N=C(C=C(N2N=C1)C(F)(F)F)C3=CC=C(C=C3)C |
Product Overview
Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate (CAS 351989-80-5), with molecular formula C17H14F3N3O2 and molecular weight 349.10 g/mol. IUPAC: ethyl 5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate.
Chemical Property Profile of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate
Property Insights of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate
The XLogP value of 3.90022 indicates that Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.49 Ų, Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate?
The CAS number of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate is 351989-80-5.
What is the molecular formula of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate?
The molecular formula of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate is C17H14F3N3O2.
What is the molecular weight of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate?
The molecular weight of Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate is 349.10 g/mol.
Where can I buy Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate?
You can request a quote for Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.