![(3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide structure](/static/products/3514/351495-40-4.webp)
(3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide
TL;DR: (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide (CAS 351495-40-4) is a chemical compound with molecular formula C16H13ClF3N5O2 and molecular weight 399.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-[4-[4-chloro-3-(trifluoromethyl)anilino]-4-oxobutan-2-ylidene]amino]pyrazine-2-carboxamide
Also Known As: (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide, N-[(E)-[4-[4-chloro-3-(trifluoromethyl)anilino]-4-oxobutan-2-ylidene]amino]pyrazine-2-carboxamide
| Molecular Formula | C16H13ClF3N5O2 |
|---|---|
| Molecular Weight | 399.07 g/mol |
| LogP | 3.2833 |
| Topological Polar Surface Area | 96.34 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 399.07098 |
| Heavy Atoms | 27 |
| Complexity | 872.1046 |
Chemical Identifiers
| CAS Number | 351495-40-4 |
|---|---|
| SMILES | C/C(=N\NC(=O)C1=NC=CN=C1)/CC(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F |
Product Overview
(3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide (CAS 351495-40-4), with molecular formula C16H13ClF3N5O2 and molecular weight 399.07 g/mol. IUPAC: N-[(E)-[4-[4-chloro-3-(trifluoromethyl)anilino]-4-oxobutan-2-ylidene]amino]pyrazine-2-carboxamide.
Chemical Property Profile of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide
Property Insights of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide
The XLogP value of 3.2833 indicates that (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.34 Ų falls within the moderate polarity range, balancing permeability and solubility for (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide. Following Lipinski's Rule of Five, (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide?
The CAS number of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide is 351495-40-4.
What is the molecular formula of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide?
The molecular formula of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide is C16H13ClF3N5O2.
What is the molecular weight of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide?
The molecular weight of (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide is 399.07 g/mol.
Where can I buy (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide?
You can request a quote for (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide?
Yes, KEHONG BIO provides custom synthesis services for (3E)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(pyrazin-2-ylcarbonyl)hydrazinylidene]butanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.