F1218-0525
TL;DR: F1218-0525 (CAS 351471-46-0) is a chemical compound with molecular formula C22H16FN5O and molecular weight 385.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(Z)-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methylideneamino]pyridine-4-carboxamide
Also Known As: F1218-0525, (Z)-N'-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)isonicotinohydrazide, N-[(Z)-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methylideneamino]pyridine-4-carboxamide, [(Z)-2-{[3-(p-fluorophenyl)-1-phenyl-4-pyrazolyl]methylene}hydrazino](4-pyridyl)methanone, N'-[(1Z)-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene]pyridine-4-carbohydrazide
| Molecular Formula | C22H16FN5O |
|---|---|
| Molecular Weight | 385.13 g/mol |
| LogP | 3.8373 |
| Topological Polar Surface Area | 72.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 385.13388 |
| Heavy Atoms | 29 |
| Complexity | 1139.0632 |
Chemical Identifiers
| CAS Number | 351471-46-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=C(C=C3)F)/C=N\NC(=O)C4=CC=NC=C4 |
Product Overview
F1218-0525 (CAS 351471-46-0), with molecular formula C22H16FN5O and molecular weight 385.13 g/mol. IUPAC: N-[(Z)-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methylideneamino]pyridine-4-carboxamide.
Chemical Property Profile of F1218-0525
Property Insights of F1218-0525
The XLogP value of 3.8373 indicates that F1218-0525 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.17 Ų falls within the moderate polarity range, balancing permeability and solubility for F1218-0525. Following Lipinski's Rule of Five, F1218-0525 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1218-0525?
The CAS number of F1218-0525 is 351471-46-0.
What is the molecular formula of F1218-0525?
The molecular formula of F1218-0525 is C22H16FN5O.
What is the molecular weight of F1218-0525?
The molecular weight of F1218-0525 is 385.13 g/mol.
Where can I buy F1218-0525?
You can request a quote for F1218-0525 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1218-0525?
Yes, KEHONG BIO provides custom synthesis services for F1218-0525 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.