Temazepam, TMS
TL;DR: Temazepam, TMS (CAS 35147-95-6) is a chemical compound with molecular formula C19H21ClN2O2Si and molecular weight 372.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-1-methyl-5-phenyl-3-trimethylsilyloxy-3H-1,4-benzodiazepin-2-one
Also Known As: Temazepam, TMS, Trimethylsilyl temazepam, Temazepam, TMS derivative, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-3-[(trimethylsilyl)oxy]-, 7-Chloro-1-methyl-5-phenyl-3-[ oxy]-1H-1,4-benzodiazepin-2 -one
| Molecular Formula | C19H21ClN2O2Si |
|---|---|
| Molecular Weight | 372.11 g/mol |
| LogP | 4.3314 |
| Topological Polar Surface Area | 41.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 372.10608 |
| Heavy Atoms | 25 |
| Complexity | 528.0 |
Chemical Identifiers
| CAS Number | 35147-95-6 |
|---|---|
| SMILES | CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O[Si](C)(C)C)C3=CC=CC=C3 |
| InChIKey | QQCHKHBRXNQGTF-UHFFFAOYSA-N |
Product Overview
Temazepam, TMS (CAS 35147-95-6), with molecular formula C19H21ClN2O2Si and molecular weight 372.11 g/mol. IUPAC: 7-chloro-1-methyl-5-phenyl-3-trimethylsilyloxy-3H-1,4-benzodiazepin-2-one.
Chemical Property Profile of Temazepam, TMS
Property Insights of Temazepam, TMS
The XLogP value of 4.3314 indicates that Temazepam, TMS is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.9 Ų, Temazepam, TMS exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Temazepam, TMS has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Temazepam, TMS?
The CAS number of Temazepam, TMS is 35147-95-6.
What is the molecular formula of Temazepam, TMS?
The molecular formula of Temazepam, TMS is C19H21ClN2O2Si.
What is the molecular weight of Temazepam, TMS?
The molecular weight of Temazepam, TMS is 372.11 g/mol.
Where can I buy Temazepam, TMS?
You can request a quote for Temazepam, TMS directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Temazepam, TMS?
Yes, KEHONG BIO provides custom synthesis services for Temazepam, TMS and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.