1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine
TL;DR: 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 351468-83-2) is a chemical compound with molecular formula C14H13ClF3N5 and molecular weight 343.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-chloro-5-(trifluoromethyl)phenyl]-2-(4,6-dimethylpyrimidin-2-yl)guanidine
Also Known As: 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-(4,6-dimethylpyrimidin-2-yl)guanidine, 1-[2-chloro-5-(trifluoromethyl)phenyl]-2-(4,6-dimethylpyrimidin-2-yl)guanidine, N'-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]-N-(4,6-DIMETHYLPYRIMIDIN-2-YL)GUANIDINE, C14H13ClF3N5
| Molecular Formula | C14H13ClF3N5 |
|---|---|
| Molecular Weight | 343.08 g/mol |
| LogP | 3.82394 |
| Topological Polar Surface Area | 76.19 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 343.08115 |
| Heavy Atoms | 23 |
| Complexity | 738.31335 |
Chemical Identifiers
| CAS Number | 351468-83-2 |
|---|---|
| SMILES | CC1=CC(=NC(=N1)N=C(N)NC2=C(C=CC(=C2)C(F)(F)F)Cl)C |
Product Overview
1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 351468-83-2), with molecular formula C14H13ClF3N5 and molecular weight 343.08 g/mol. IUPAC: 1-[2-chloro-5-(trifluoromethyl)phenyl]-2-(4,6-dimethylpyrimidin-2-yl)guanidine.
Chemical Property Profile of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine
Property Insights of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine
The XLogP value of 3.82394 indicates that 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.19 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine. Following Lipinski's Rule of Five, 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine?
The CAS number of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine is 351468-83-2.
What is the molecular formula of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine?
The molecular formula of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine is C14H13ClF3N5.
What is the molecular weight of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine?
The molecular weight of 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine is 343.08 g/mol.
Where can I buy 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine?
You can request a quote for 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-Chloro-5-(trifluoromethyl)phenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.