AE-848/14138018
TL;DR: AE-848/14138018 (CAS 351438-27-2) is a chemical compound with molecular formula C25H26F3N5O and molecular weight 469.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-benzylpiperazin-1-yl)-[5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]methanone
Also Known As: AE-848/14138018, (4-benzylpiperazin-1-yl)(5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl)methanone, (4-Benzylpiperazin-1-yl)-[5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]methanone, 2-[(4-benzylpiperazin-1-yl)carbonyl]-5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine, (4-benzylpiperazin-1-yl)-[5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]methanone
| Molecular Formula | C25H26F3N5O |
|---|---|
| Molecular Weight | 469.21 g/mol |
| LogP | 4.5014 |
| Topological Polar Surface Area | 53.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 469.20895 |
| Heavy Atoms | 34 |
| Complexity | 1124.4578 |
Chemical Identifiers
| CAS Number | 351438-27-2 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC=CC=C2)C(=O)C3=NN4C(CC(NC4=C3)C5=CC=CC=C5)C(F)(F)F |
Product Overview
AE-848/14138018 (CAS 351438-27-2), with molecular formula C25H26F3N5O and molecular weight 469.21 g/mol. IUPAC: (4-benzylpiperazin-1-yl)-[5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]methanone.
Chemical Property Profile of AE-848/14138018
Property Insights of AE-848/14138018
The XLogP value of 4.5014 indicates that AE-848/14138018 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.4 Ų, AE-848/14138018 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AE-848/14138018 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AE-848/14138018?
The CAS number of AE-848/14138018 is 351438-27-2.
What is the molecular formula of AE-848/14138018?
The molecular formula of AE-848/14138018 is C25H26F3N5O.
What is the molecular weight of AE-848/14138018?
The molecular weight of AE-848/14138018 is 469.21 g/mol.
Where can I buy AE-848/14138018?
You can request a quote for AE-848/14138018 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AE-848/14138018?
Yes, KEHONG BIO provides custom synthesis services for AE-848/14138018 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.