![2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol structure](/static/products/351/351422-45-2.png)
2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol
TL;DR: 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol (CAS 351422-45-2) is a chemical compound with molecular formula C13H14F3N3O and molecular weight 285.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-methyl-2-[[2-(trifluoromethyl)quinazolin-4-yl]amino]propan-1-ol
Also Known As: 4-substituted quinazoline 27, J1.536.353C, 2-methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol, 2-[2-(Trifluoromethyl)quinazoline-4-ylamino]-2-methyl-1-propanol, 2-methyl-2-((2-(trifluoromethyl)quinazolin-4-yl)amino)propan-1-ol
| Molecular Formula | C13H14F3N3O |
|---|---|
| Molecular Weight | 285.11 g/mol |
| LogP | 2.8314 |
| Topological Polar Surface Area | 58.04 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 285.1089 |
| Heavy Atoms | 20 |
| Complexity | 625.7778 |
Chemical Identifiers
| CAS Number | 351422-45-2 |
|---|---|
| SMILES | CC(C)(CO)NC1=NC(=NC2=CC=CC=C21)C(F)(F)F |
Product Overview
2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol (CAS 351422-45-2), with molecular formula C13H14F3N3O and molecular weight 285.11 g/mol. IUPAC: 2-methyl-2-[[2-(trifluoromethyl)quinazolin-4-yl]amino]propan-1-ol.
Chemical Property Profile of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol
Property Insights of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol
The XLogP value of 2.8314 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol. With a topological polar surface area (TPSA) of 58.04 Ų, 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol?
The CAS number of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol is 351422-45-2.
What is the molecular formula of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol?
The molecular formula of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol is C13H14F3N3O.
What is the molecular weight of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol?
The molecular weight of 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol is 285.11 g/mol.
Where can I buy 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol?
You can request a quote for 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol?
Yes, KEHONG BIO provides custom synthesis services for 2-Methyl-2-{[2-(trifluoromethyl)quinazolin-4-yl]amino}propan-1-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.