4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole
TL;DR: 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole (CAS 351333-15-8) is a chemical compound with molecular formula C10H6ClFN2O and molecular weight 224.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-chloropyrazol-1-yl)-(4-fluorophenyl)methanone
Also Known As: TimTec1_002372, N-Benzoylpyrazole deriv., 1, 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole, BAS 02052920, (4-chloropyrazol-1-yl)-(4-fluorophenyl)methanone
| Molecular Formula | C10H6ClFN2O |
|---|---|
| Molecular Weight | 224.02 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 34.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 224.01527 |
| Heavy Atoms | 15 |
| Complexity | 244.0 |
Chemical Identifiers
| CAS Number | 351333-15-8 |
|---|---|
| SMILES | C1=CC(=CC=C1C(=O)N2C=C(C=N2)Cl)F |
| InChIKey | FTDJTWUEACFTRX-UHFFFAOYSA-N |
Product Overview
4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole (CAS 351333-15-8), with molecular formula C10H6ClFN2O and molecular weight 224.02 g/mol. IUPAC: (4-chloropyrazol-1-yl)-(4-fluorophenyl)methanone.
Chemical Property Profile of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole
Property Insights of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole. With a topological polar surface area (TPSA) of 34.9 Ų, 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole?
The CAS number of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole is 351333-15-8.
What is the molecular formula of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole?
The molecular formula of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole is C10H6ClFN2O.
What is the molecular weight of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole?
The molecular weight of 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole is 224.02 g/mol.
Where can I buy 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole?
You can request a quote for 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole?
Yes, KEHONG BIO provides custom synthesis services for 4-chloro-1-(4-fluorobenzoyl)-1H-pyrazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.