N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide structure

N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide

TL;DR: N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide (CAS 351329-97-0) is a chemical compound with molecular formula C22H14N4O2S and molecular weight 398.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(2-hydroxy-1H-indol-3-yl)imino]-2-thiophen-2-ylquinoline-4-carboxamide

Also Known As: N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide, (E)-N'-(2-oxoindolin-3-ylidene)-2-(thiophen-2-yl)quinoline-4-carbohydrazide, N'-[(3E)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(thiophen-2-yl)quinoline-4-carbohydrazide

CAS: 351329-97-0
Molecular Formula C22H14N4O2S
Molecular Weight 398.08 g/mol
LogP 6.0743
Topological Polar Surface Area 90.7 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 398.08374
Heavy Atoms 29
Complexity 1387.0193

Chemical Identifiers

CAS Number 351329-97-0
SMILES C1=CC=C2C(=C1)C(=C(N2)O)N=NC(=O)C3=CC(=NC4=CC=CC=C43)C5=CC=CS5

Product Overview

N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide (CAS 351329-97-0), with molecular formula C22H14N4O2S and molecular weight 398.08 g/mol. IUPAC: N-[(2-hydroxy-1H-indol-3-yl)imino]-2-thiophen-2-ylquinoline-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide

XLogP
6.0743
TPSA (Topological Polar Surface Area)
90.7
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
29
Complexity
1387.0193
Exact Mass
398.08374
Monoisotopic Mass
398.08374
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide

The XLogP value of 6.0743 indicates that N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.7 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide. Following Lipinski's Rule of Five, N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide?

The CAS number of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide is 351329-97-0.

What is the molecular formula of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide?

The molecular formula of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide is C22H14N4O2S.

What is the molecular weight of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide?

The molecular weight of N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide is 398.08 g/mol.

Where can I buy N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide?

You can request a quote for N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide?

Yes, KEHONG BIO provides custom synthesis services for N'-(2-oxoindol-3-yl)-2-thiophen-2-ylquinoline-4-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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