1-Demethylmetergoline structure

1-Demethylmetergoline

TL;DR: 1-Demethylmetergoline (CAS 35121-59-6) is a chemical compound with molecular formula C24H27N3O2 and molecular weight 389.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

benzyl N-[[(6aR,9S)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]methyl]carbamate

Also Known As: 1-Demethylmetergoline, 1-Demethylmethergoline, Benzyl hydrogen [(6-methylergolin-8-yl)methyl]carbonimidate, Benzyl hydrogen {[(10xi)-6-methylergolin-8beta-yl]methyl}carbonimidate, Carbamic acid, (((8beta)-6-methylergolin-8-yl)methyl)-, phenylmethyl ester

CAS: 35121-59-6
Molecular Formula C24H27N3O2
Molecular Weight 389.21 g/mol
LogP 3.8
Topological Polar Surface Area 57.4 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 5
Exact Mass 389.21033
Heavy Atoms 29
Complexity 578.0

Chemical Identifiers

CAS Number 35121-59-6
SMILES CN1C[C@@H](CC2[C@H]1CC3=CNC4=CC=CC2=C34)CNC(=O)OCC5=CC=CC=C5
InChIKey REJFPXMKRRYBSC-PQBSNVOHSA-N

Product Overview

1-Demethylmetergoline (CAS 35121-59-6), with molecular formula C24H27N3O2 and molecular weight 389.21 g/mol. IUPAC: benzyl N-[[(6aR,9S)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]methyl]carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1-Demethylmetergoline

XLogP
3.8
TPSA (Topological Polar Surface Area)
57.4
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
5
Heavy Atoms
29
Complexity
578.0
Exact Mass
389.21033
Monoisotopic Mass
389.21033
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-Demethylmetergoline

The XLogP value of 3.8 indicates that 1-Demethylmetergoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.4 Ų, 1-Demethylmetergoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Demethylmetergoline has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-Demethylmetergoline?

The CAS number of 1-Demethylmetergoline is 35121-59-6.

What is the molecular formula of 1-Demethylmetergoline?

The molecular formula of 1-Demethylmetergoline is C24H27N3O2.

What is the molecular weight of 1-Demethylmetergoline?

The molecular weight of 1-Demethylmetergoline is 389.21 g/mol.

Where can I buy 1-Demethylmetergoline?

You can request a quote for 1-Demethylmetergoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-Demethylmetergoline?

Yes, KEHONG BIO provides custom synthesis services for 1-Demethylmetergoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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