18-Hydroxy-11-deoxycortisol
TL;DR: 18-Hydroxy-11-deoxycortisol (CAS 35121-42-7) is a chemical compound with molecular formula C21H30O5 and molecular weight 362.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: 18-Hydroxy-11-deoxycortisol, 11-desoxy-17,18-dihydroxycorticosterone, 17,18,21-Trihydroxypregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 17,18,21-trihydroxy-, Pregn-4-ene-3,20-dione,17,18,21-trihydroxy
| Molecular Formula | C21H30O5 |
|---|---|
| Molecular Weight | 362.21 g/mol |
| LogP | 1.7832 |
| Topological Polar Surface Area | 94.83 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.20932 |
| Heavy Atoms | 26 |
| Complexity | 669.31256 |
Chemical Identifiers
| CAS Number | 35121-42-7 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)CO |
Product Overview
18-Hydroxy-11-deoxycortisol (CAS 35121-42-7), with molecular formula C21H30O5 and molecular weight 362.21 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 18-Hydroxy-11-deoxycortisol
Property Insights of 18-Hydroxy-11-deoxycortisol
The XLogP value of 1.7832 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 18-Hydroxy-11-deoxycortisol. The TPSA of 94.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 18-Hydroxy-11-deoxycortisol. Following Lipinski's Rule of Five, 18-Hydroxy-11-deoxycortisol has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 18-Hydroxy-11-deoxycortisol?
The CAS number of 18-Hydroxy-11-deoxycortisol is 35121-42-7.
What is the molecular formula of 18-Hydroxy-11-deoxycortisol?
The molecular formula of 18-Hydroxy-11-deoxycortisol is C21H30O5.
What is the molecular weight of 18-Hydroxy-11-deoxycortisol?
The molecular weight of 18-Hydroxy-11-deoxycortisol is 362.21 g/mol.
Where can I buy 18-Hydroxy-11-deoxycortisol?
You can request a quote for 18-Hydroxy-11-deoxycortisol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 18-Hydroxy-11-deoxycortisol?
Yes, KEHONG BIO provides custom synthesis services for 18-Hydroxy-11-deoxycortisol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.