JARID1B Demethylase Inhibitor structure

JARID1B Demethylase Inhibitor

TL;DR: JARID1B Demethylase Inhibitor (CAS 351190-46-0) is a chemical compound with molecular formula C16H8F3N3S and molecular weight 331.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-3-pyridin-4-yl-2-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]prop-2-enenitrile

Also Known As: JARID1B Demethylase Inhibitor, (E)-3-pyridin-4-yl-2-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]prop-2-enenitrile, 3-Pyridin-4-yl-2-(5-trifluoromethyl-benzothiazol-2-yl)-acrylonitrile

CAS: 351190-46-0
Molecular Formula C16H8F3N3S
Molecular Weight 331.04 g/mol
LogP 4.77428
Topological Polar Surface Area 49.57 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 331.0391
Heavy Atoms 23
Complexity 921.1337

Chemical Identifiers

CAS Number 351190-46-0
SMILES C1=CC2=C(C=C1C(F)(F)F)N=C(S2)/C(=C/C3=CC=NC=C3)/C#N

Product Overview

JARID1B Demethylase Inhibitor (CAS 351190-46-0), with molecular formula C16H8F3N3S and molecular weight 331.04 g/mol. IUPAC: (E)-3-pyridin-4-yl-2-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]prop-2-enenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of JARID1B Demethylase Inhibitor

XLogP
4.77428
TPSA (Topological Polar Surface Area)
49.57
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
23
Complexity
921.1337
Exact Mass
331.0391
Monoisotopic Mass
331.0391
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of JARID1B Demethylase Inhibitor

The XLogP value of 4.77428 indicates that JARID1B Demethylase Inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.57 Ų, JARID1B Demethylase Inhibitor exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, JARID1B Demethylase Inhibitor has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of JARID1B Demethylase Inhibitor?

The CAS number of JARID1B Demethylase Inhibitor is 351190-46-0.

What is the molecular formula of JARID1B Demethylase Inhibitor?

The molecular formula of JARID1B Demethylase Inhibitor is C16H8F3N3S.

What is the molecular weight of JARID1B Demethylase Inhibitor?

The molecular weight of JARID1B Demethylase Inhibitor is 331.04 g/mol.

Where can I buy JARID1B Demethylase Inhibitor?

You can request a quote for JARID1B Demethylase Inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for JARID1B Demethylase Inhibitor?

Yes, KEHONG BIO provides custom synthesis services for JARID1B Demethylase Inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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