3-Fluoro-4-methoxybenzyl chloride structure

3-Fluoro-4-methoxybenzyl chloride

TL;DR: 3-Fluoro-4-methoxybenzyl chloride (CAS 351-52-0) is a chemical compound with molecular formula C8H8ClFO and molecular weight 174.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(chloromethyl)-2-fluoro-1-methoxybenzene

Also Known As: 3-Fluoro-4-methoxybenzyl chloride, null, 3-fluoro-4-methoxybenzylchloride, 4-(chloromethyl)-2-fluoro-1-methoxybenzene, 4-Chlormethyl-2-fluor-anisol

CAS: 351-52-0
Molecular Formula C8H8ClFO
Molecular Weight 174.02 g/mol
LogP 2.5731
Topological Polar Surface Area 9.23 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 2
Exact Mass 174.02477
Heavy Atoms 11
Complexity 249.84741

Chemical Identifiers

CAS Number 351-52-0
SMILES COC1=C(C=C(C=C1)CCl)F

Product Overview

3-Fluoro-4-methoxybenzyl chloride (CAS 351-52-0), with molecular formula C8H8ClFO and molecular weight 174.02 g/mol. IUPAC: 4-(chloromethyl)-2-fluoro-1-methoxybenzene.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3-Fluoro-4-methoxybenzyl chloride

XLogP
2.5731
TPSA (Topological Polar Surface Area)
9.23
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
2
Heavy Atoms
11
Complexity
249.84741
Exact Mass
174.02477
Monoisotopic Mass
174.02477
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-Fluoro-4-methoxybenzyl chloride

The XLogP value of 2.5731 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Fluoro-4-methoxybenzyl chloride. With a topological polar surface area (TPSA) of 9.23 Ų, 3-Fluoro-4-methoxybenzyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Fluoro-4-methoxybenzyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-Fluoro-4-methoxybenzyl chloride?

The CAS number of 3-Fluoro-4-methoxybenzyl chloride is 351-52-0.

What is the molecular formula of 3-Fluoro-4-methoxybenzyl chloride?

The molecular formula of 3-Fluoro-4-methoxybenzyl chloride is C8H8ClFO.

What is the molecular weight of 3-Fluoro-4-methoxybenzyl chloride?

The molecular weight of 3-Fluoro-4-methoxybenzyl chloride is 174.02 g/mol.

Where can I buy 3-Fluoro-4-methoxybenzyl chloride?

You can request a quote for 3-Fluoro-4-methoxybenzyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-Fluoro-4-methoxybenzyl chloride?

Yes, KEHONG BIO provides custom synthesis services for 3-Fluoro-4-methoxybenzyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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