2'-deoxy-2-thiouridine
TL;DR: 2'-deoxy-2-thiouridine (CAS 35059-12-2) is a chemical compound with molecular formula C9H12N2O4S and molecular weight 244.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one
Also Known As: 2'-deoxy-2-thiouridine, 2-Thiodeoxyuridine, 2-Thio 2'-Deoxyuridine, 2-thio-2'-deoxyuridine, 2 -Deoxy-2-thiouridine
| Molecular Formula | C9H12N2O4S |
|---|---|
| Molecular Weight | 244.05 g/mol |
| LogP | -0.45341 |
| Topological Polar Surface Area | 87.48 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 244.05177 |
| Heavy Atoms | 16 |
| Complexity | 482.8876 |
Chemical Identifiers
| CAS Number | 35059-12-2 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=S)CO)O |
Product Overview
2'-deoxy-2-thiouridine (CAS 35059-12-2), with molecular formula C9H12N2O4S and molecular weight 244.05 g/mol. IUPAC: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one.
Chemical Property Profile of 2'-deoxy-2-thiouridine
Property Insights of 2'-deoxy-2-thiouridine
The XLogP value of -0.45341 indicates that 2'-deoxy-2-thiouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 87.48 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-deoxy-2-thiouridine. Following Lipinski's Rule of Five, 2'-deoxy-2-thiouridine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-deoxy-2-thiouridine?
The CAS number of 2'-deoxy-2-thiouridine is 35059-12-2.
What is the molecular formula of 2'-deoxy-2-thiouridine?
The molecular formula of 2'-deoxy-2-thiouridine is C9H12N2O4S.
What is the molecular weight of 2'-deoxy-2-thiouridine?
The molecular weight of 2'-deoxy-2-thiouridine is 244.05 g/mol.
Where can I buy 2'-deoxy-2-thiouridine?
You can request a quote for 2'-deoxy-2-thiouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-deoxy-2-thiouridine?
Yes, KEHONG BIO provides custom synthesis services for 2'-deoxy-2-thiouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.